I've made squinty eyes at enough ADMIXTURE charts by now that I'm starting to see the trends that keep popping up under different types of runs (reference populations, K numbers, etc). While things begin to break down at high K values, they remain pretty consistent at low K values. I am almost always ~10% Near Eastern (or Middle Eastern, or West Asian, or whatever you want to call it), ~40% South European, and ~50% North European. I think I can take at least that much as gospel at this point. When Native Americans are in the mix, I am always at least 1% Native American. I also often get blips of South/East Asian, but I am still not convinced that that one isn't just noise.
Razib's latest ADMIXTURE run, which I've included here, is typical of what I just described above. It is also almost exactly what came up for me at Dodecad (DOD493). The "Brown Dude" I've included at the bottom of the chart is my boyfriend. His parents are from Karnataka, in southwest India, and his results don't surprise me. I am used to looking at Bengali ADMIXTURE because of the samples in Razib's dataset, and BD's results differ mainly in that he has more West Asian and less East Asian. I'd say that's pretty geographically sound.
On a personal note, 23andMe thinks that there's a 0% possibility that BD and I are related, so that's a relief. He's also not a carrier for the two diseases that I'm a carrier for, which is also a relief. We both have the genes for wet earwax, photic sneeze reflex, and fast caffeine metabolism (I know you were dying to know), so our children will likely be brown-eyed, sticky-eared, constantly sneezing coffee guzzlers, right?
Field of Science
-
-
From Valley Forge to the Lab: Parallels between Washington's Maneuvers and Drug Development4 weeks ago in The Curious Wavefunction
-
Political pollsters are pretending they know what's happening. They don't.4 weeks ago in Genomics, Medicine, and Pseudoscience
-
-
Course Corrections5 months ago in Angry by Choice
-
-
The Site is Dead, Long Live the Site2 years ago in Catalogue of Organisms
-
The Site is Dead, Long Live the Site2 years ago in Variety of Life
-
Does mathematics carry human biases?4 years ago in PLEKTIX
-
-
-
-
A New Placodont from the Late Triassic of China5 years ago in Chinleana
-
Posted: July 22, 2018 at 03:03PM6 years ago in Field Notes
-
Bryophyte Herbarium Survey7 years ago in Moss Plants and More
-
Harnessing innate immunity to cure HIV8 years ago in Rule of 6ix
-
WE MOVED!8 years ago in Games with Words
-
Do social crises lead to religious revivals? Nah!8 years ago in Epiphenom
-
-
-
-
post doc job opportunity on ribosome biochemistry!9 years ago in Protein Evolution and Other Musings
-
Growing the kidney: re-blogged from Science Bitez9 years ago in The View from a Microbiologist
-
-
Blogging Microbes- Communicating Microbiology to Netizens10 years ago in Memoirs of a Defective Brain
-
-
-
The Lure of the Obscure? Guest Post by Frank Stahl12 years ago in Sex, Genes & Evolution
-
-
Lab Rat Moving House13 years ago in Life of a Lab Rat
-
Goodbye FoS, thanks for all the laughs13 years ago in Disease Prone
-
-
Slideshow of NASA's Stardust-NExT Mission Comet Tempel 1 Flyby13 years ago in The Large Picture Blog
-
in The Biology Files
5 comments:
Markup Key:
- <b>bold</b> = bold
- <i>italic</i> = italic
- <a href="http://www.fieldofscience.com/">FoS</a> = FoS
Anonymous comments will NOT be approved. You must include a name at the very least.
Subscribe to:
Post Comments (Atom)
re: ear wax, you are homozygote, so that is correct. if you were heterozygote you'd have to look at BD to double check of course.
ReplyDeleteBD consistently has the west asian type element in my runs. i think this is something common the west coast of south asia, north to south.
The Dar is heterozygotic for wet earwax. I just like saying "brown-eyed, sticky-eared children". Before 23andMe I didn't know there were people with dry earwax.
ReplyDeleteBefore 23andMe I didn't know there were people with dry earwax.
ReplyDeletemost people in east asia have it. my family is heterozygote. one of my siblings and my mom has it. the rest of us do not.
Is admixture only interesting when you have multi-continental ancestry? E.g., my daughter recently did 23-and-Me and the results just said all northern European, mostly Celtic, but no discrimination between Welsh, Irish, Scottish, or French. Where do you get that kind of breakdown? thanks,
ReplyDelete23andMe has very underwhelming ancestry results. To get better results you have to do an independent analysis. I am lucky in that I have several genetics geek friends to do that kind of stuff for me (I don't have the slightest clue how to run ADMIXTURE). You can keep an eye on several genetics blogs (there are tons, Dodecad is a big one) and wait for calls for data that apply to you.
ReplyDelete